By means of GMI reporter
Could a leaf from one of the oldest trees in the world unlock new possibilities in stroke recovery? Discover the potential of ginkgo biloba in improving cognitive healing after stroke.
In an illuminating discovery, researchers have discovered that ginkgo bilobaan ancient tree revered for its medicinal properties may hold the key to improved cognitive recovery after ischemic illness heart attack. This revelation comes from research ready for presentation at the 2024 International Stroke Conference, orchestrated by the American Stroke Association.
Study design: a closer look at methodology
The focus of the study was the efficacy of ginkgo diterpene lactone meglumine (GDLM), an active ingredient of ginkgo biloba, in aiding cognitive recovery after stroke. This multicenter study, conducted at 100 centers in China, involved 3,163 stroke survivors. These individuals suffer from mild to moderate ischemia heart attack, started treatment within 48 hours of their stroke incident. They were randomized to receive 25 mg intravenous GDLM or a placebo daily for two weeks. Cognitive function was rigorously assessed at baseline, after 14 days, and again after 90 days using the Montreal Cognitive Assessment Scale (MoCA).
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Results and Findings: The Cognitive Impact of Ginkgo
The findings were promising: Those treated with GDLM showed more significant cognitive improvements than the placebo group at both 14 days and 90 days. Specifically, the GDLM group showed an average cognitive score increase of 3.93 points after 14 days and 5.51 points after 90 days, indicating a tangible improvement in cognitive function.
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The science behind GDLM
The potential of GDLM extends beyond mere cognitive improvement. Its neuroprotective properties, as explained by Anxin Wang, Ph.D., include vasodilation, improved oxygen tolerance, and improved cerebral blood flow. Furthermore, its antioxidant, anti-inflammatory and anti-apoptotic properties collectively contribute to its therapeutic potency. Preliminary laboratory studies also indicate the role of GDLM in preventing neurodegenerative disorders such as Parkinson’s and Alzheimer’s diseases.
Navigating the path of complementary medicine
The incorporation of ginkgo biloba in stroke recovery, although promising, cautious optimism is necessary. Sheryl L. Chow, Pharm.D., underlines the importance of integrating such complementary treatments within the broader healthcare framework to ensure safety and efficacy. The study findings, while compelling, call for further validation through independent studies to strengthen the role of GDLM in cognitive rehabilitation after stroke.
Future directions: from research to real-world application
Although the study results are specific to a Chinese target group, they pave the way for global research efforts to investigate the universal applicability of GDLM in stroke recovery. The quest for FDA approval and integration into standard care regimens after stroke remains a critical future milestone.
To learn more about the benefits of gingko biloba, visit our database on this topic here.
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To learn more about natural approaches to stroke recovery, visit our database on this topic here.
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References
1. American Heart Association. “Active components of ginkgo biloba may improve early cognitive recovery after stroke.” News from the American Heart Association, February 1, 2024.
Disclaimer: This article is not intended to provide medical advice, diagnosis, or treatment. The opinions expressed here do not necessarily reflect those of GreenMedInfo or its employees.
Source: GreenMedInfo
This article is copyrighted by GreenMedInfo LLC, 2024
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